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1

Peptide Therapeutics

Vorherr, Thomas

Journal:

Bioorganic & Medicinal Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 225 KB

english, 2018

2

Differential and multiple binding of signal transducing molecules to the ITAMs of the TCR-ζ chain

Georg Zenner, Thomas Vorherr, Tomas Mustelin, Paul Burn

Journal:

Journal of Cellular Biochemistry

Année:

1996

Langue:

english

Fichier:

PDF, 897 KB

english, 1996

3

NMR Solution Structure of Phospholamban

Stefanie Lamberth, Holger Schmid, Martin Muenchbach, Thomas Vorherr, Joachim Krebs, Ernesto Carafoli, Christian Griesinger

Journal:

Helvetica Chimica Acta

Année:

2000

Langue:

english

Fichier:

PDF, 1.92 MB

english, 2000

4

ChemInform Abstract: NMR Solution Structure of Phospholamban

Stefanie Lamberth, Holger Schmid, Martin Muenchbach, Thomas Vorherr, Joachim Krebs, Ernesto Carafoli, Christian Griesinger

Journal:

Année:

2000

Fichier:

PDF, 25 KB

2000

5

A Very Bright Future for CGMP-Manufacturing of Peptides

Journal:

Année:

2005

Fichier:

PDF, 7 KB

2005

6

ChemInform Abstract: Recent Developments to Encourage the Synthesis of Complex Peptides

Journal:

Année:

2011

Fichier:

PDF, 18 KB

2011

7

Single-Centre Model for the Active Site of α-Chymotrypsin

Thomas Vorherr, Karl-Heinz Altmann, Manfred Mutter

Journal:

Helvetica Chimica Acta

Année:

1986

Langue:

english

Fichier:

PDF, 301 KB

english, 1986

8

Approaches to Synthetic Vaccines Design of Epitope-Containing Amphiphilic Peptides Matching the Antigenic Structure in the Native Protein

Manfred Mutter, Karl-Heinz Altmann, Klaus Müller, StéPhane Vuilleumier, Thomas Vorherr

Journal:

Helvetica Chimica Acta

Année:

1986

Langue:

english

Fichier:

PDF, 870 KB

english, 1986

9

Phospho-serine and phospho-threonine building blocks for the synthesis of phosphorylated peptides by the Fmoc solid phase strategy

Thomas Vorherr, Willi Bannwarth

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

1995

Langue:

english

Fichier:

PDF, 249 KB

english, 1995

10

Peptide thioester preparation based on an N-S acyl shift reaction mediated by a thiol ligation auxiliary

Toru Kawakami, Megumi Sumida, Ken’ichiroh Nakamura, Thomas Vorherr, Saburo Aimoto

Journal:

Tetrahedron Letters

Année:

2005

Langue:

english

Fichier:

PDF, 108 KB

english, 2005

11

The calmodulin-binding site of the plasma membrane Ca2+ pump interacts with the transduction domain of the enzyme

Rocco Falchetto, Thomas Vorherr, Ernesto Carafoli

Journal:

Protein Science

Année:

1992

Langue:

english

Fichier:

PDF, 1.86 MB

english, 1992

12

Total synthesis and functional properties of the membrane-intrinsic protein phospholamban

Thomas Vorherr, Ernesto Carafoli, Antoni Wrzosek, Michele Chiesi

Journal:

Protein Science

Année:

1993

Langue:

english

Fichier:

PDF, 1.59 MB

english, 1993

13

Synthesis and application of an auxiliary group for chemical ligation at the X-gly site

Jean Vizzavona, Fritz Dick, Thomas Vorherr

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2002

Langue:

english

Fichier:

PDF, 88 KB

english, 2002

14

Calmodulin-binding domains: just two faced or multi-faceted?

Peter James, Thomas Vorherr, Ernesto Carafoli

Journal:

Trends in Biochemical Sciences

Année:

1995

Langue:

english

Fichier:

PDF, 1.85 MB

english, 1995

15

Application of the allyloxycarbonyl protecting group for the indole of Trp in solid-phase peptide synthesis

THOMAS VORHERR, ARNOLD TRZECIAK, WILLI BANNWARTH

Journal:

Chemical Biology & Drug Design

Année:

1996

Langue:

english

Fichier:

PDF, 496 KB

english, 1996

16

Identification of two domains which mediate the binding of activating phospholipids to the plasma-membrane Ca2+ pump

Peter BRODIN, Rocco FALCHETTO, Thomas VORHERR, Ernesto CARAFOLI

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 899 KB

english, 1992

17

Construction and molecular dynamics simulation of calmodulin in the extended and in a bent conformation

Thomas VORHERR, Oliver KESSLER, Alan MARK, Ernesto CARAFOLI

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 940 KB

english, 1992

18

The Calmodulin-binding Domain of the Inducible (Macrophage) Nitric Oxide Synthase

John Anagli, Francesco Hofmann, Manfredo Quadroni, Thomas Vorherr, Ernesto Carafoli

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 897 KB

english, 1995

19

Identification and primary structure of a calbindin 9K binding domain in the plasma membrane Ca2+ pump

Peter James, Thomas Vorherr, Eva Thulin, Sture Forsen, Ernesto Carafoli

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 380 KB

english, 1991

20

The Molecular Basis of the Modulation of the Plasma Membrane Calcium Pump by Calmodulin

ERNESTO CARAFOLI, FELIX KESSLER, ROCCO FALCHETTO, ROGER HEIM, MANFREDO QUADRONI, JOACHIM KREBS, EMANUEL E. STREHLER, THOMAS VORHERR

Journal:

Annals of the New York Academy of Sciences

Année:

1992

Langue:

english

Fichier:

PDF, 1.11 MB

english, 1992

21

The Fourth Immunoglobulin-like Domain of NCAM Contains a Carbohydrate Recognition Domain for Oligomannosidic Glycans Implicated in Association with L1 and Neurite Outgrowth

Rüdiger Horstkorte, Melitta Schachner, Josef Peter Magyar, Thomas Vorherr and Brigitte Schmitz

Journal:

The Journal of Cell Biology

Année:

1993

Langue:

english

Fichier:

PDF, 3.60 MB

english, 1993

22

Primary structure of the cAMP-dependent phosphorylation site of the plasma membrane calcium pump

James, Peter H., Pruschy, Martin, Vorherr, Thomas E., Penniston, John T., Carafoli, Ernesto

Journal:

Année:

1989

Langue:

english

Fichier:

PDF, 1.28 MB

english, 1989

23

Interaction of calmodulin with the calmodulin binding domain of the plasma membrane calcium pump

Vorherr, Thomas, James, Peter, Krebs, Joachim, Enyedi, Agnes, McCormick, Daniel J., Penniston, John T., Carafoli, Ernesto

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 2.08 MB

english, 1990

24

Small-angle x-ray scattering study of calmodulin bound to two peptides corresponding to parts of the calmodulin-binding domain of the plasma membrane calcium pump

Kataoka, Mikio, Head, James F., Vorherr, Thomas, Krebs, Joachim, Carafoli, Ernesto

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 603 KB

english, 1991

25

Binding of calcium by calmodulin: influence of the calmodulin binding domain of the plasma membrane calcium pump

Yazawa, Michio, Vorherr, Thomas, James, Peter, Carafoli, Ernesto, Yagi, Koichi

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 699 KB

english, 1992

26

Fluorescence energy transfer analysis of calmodulin.cntdot.peptide complexes

Chapman, Edwin R., Alexander, Kenneth, Vorherr, Thomas, Carafoli, Ernesto, Storm, Daniel R.

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 822 KB

english, 1992

27

Mapping of functional domains in the plasma membrane calcium pump using trypsin proteolysis

Zvaritch, E., James, Peter, Vorherr, Thomas, Falchetto, Rocco, Modyanov, N., Carafoli, Ernesto

Journal:

Année:

1990

Langue:

english

Fichier:

PDF, 1.75 MB

english, 1990

28

Determination of Homonuclear 13 C− 13 C J Couplings between Aliphatic Carbon Atoms in Perdeuterated Proteins

Hennig, Mirko, Ott, Dagmar, Schulte, Petra, Löwe, Ralf, Krebs, Joachim, Vorherr, Thomas, Bermel, Wolfgang, Schwalbe, Harald, Griesinger, Christian

Journal:

Journal of the American Chemical Society

Année:

1997

Langue:

english

Fichier:

PDF, 93 KB

english, 1997

29

Regulation of the calcium ion pump of sarcoplasmic reticulum: Reversible inhibition by phospholamban and by the calmodulin binding domain of the plasma membrane calcium pump

Vorherr, Thomas, Chiesi, Michele, Schwaller, Roland, Carafoli, Ernesto

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 768 KB

english, 1992

30

NMR Solution Structure of a Complex of Calmodulin with a Binding Peptide of the Ca 2+ Pump †,‡

Elshorst, Bettina, Hennig, Mirko, Försterling, Holger, Diener, Alexander, Maurer, Marcus, Schulte, Petra, Schwalbe, Harald, Griesinger, Christian, Krebs, Joachim, Schmid, Holger, Vorherr, Thomas, Cara

Journal:

Année:

1999

Langue:

english

Fichier:

PDF, 686 KB

english, 1999

31

The calmodulin binding domain of nitric oxide synthase and adenylyl cyclase

Vorherr, Thomas, Knoepfel, Lea, Hofmann, Francesco, Mollner, Stefan, Pfeuffer, Thomas, Carafoli, Ernesto

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 1.48 MB

english, 1993

32

Study of calmodulin binding to the alternatively spliced C-terminal domain of the plasma membrane calcium pump

Kessler, Felix, Falchetto, Rocco, Heim, Roger, Meili, Ruedi, Vorherr, Thomas, Strehler, Emanuel E., Carafoli, Ernesto

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 1.94 MB

english, 1992

33

Phospholamban is related to the autoinhibitory domain of the plasma membrane calcium-pumping ATPase

Chiesi, Michele, Vorherr, Thomas, Falchetto, Rocco, Waelchli, Chantal, Carafoli, Ernesto

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 1.32 MB

english, 1991

34

Synthetic peptides corresponding to the calmodulin-binding domains of skeletal muscle myosin light chain kinase and human erythrocyte calcium pump interact with and permeabilize liposomes and cell membranes

Eshel, Yoav, Shai, Yechiel, Vorherr, Thomas, Carafoli, Ernesto, Salomon, Yoram

Journal:

Année:

1993

Langue:

english

Fichier:

PDF, 1017 KB

english, 1993

35

A Detailed Investigation on Conformation, Permeability and PK Properties of Two Related Cyclohexapeptides

Lewis, Ian, Schaefer, Michael, Wagner, Trixie, Oberer, Lukas, Sager, Emine, Wipfli, Peter, Vorherr, Thomas

Journal:

International Journal of Peptide Research and Therapeutics

Année:

2015

Langue:

english

Fichier:

PDF, 993 KB

english, 2015

36

Characterization of a 21 amino acid peptide sequence of the laminin G2 domain that is involved in HNK-1 carbohydrate binding and cell adhesion

Hall, Heike, Vorherr, Thomas, Schachner, Melitta

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 3.59 MB

english, 1995

37

Modifying peptides to enhance permeability

Vorherr, Thomas

Journal:

Future Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.27 MB

english, 2015

38

Towards Intracellular Delivery of Peptides

Marzinzik, Andreas L., Vorherr, Thomas E.

Journal:

CHIMIA International Journal for Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 181 KB

english, 2013

39

Photoaffinity labeling study of the interaction of calmodulin with the plasma membrane calcium pump

Vorherr, Thomas, Quadroni, Manfredo, Krebs, Joachim, Carafoli, Ernesto

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 1.31 MB

english, 1992

40

The Construction of New Proteins. II. Design, Synthesis and Conformational Studies of Folding Units with βαβ-Topology

Mutter, Manfred, Altmann, Karl-Heinz, Vorherr, Thomas

Journal:

Zeitschrift für Naturforschung B

Année:

1986

Langue:

english

Fichier:

PDF, 6.71 MB

english, 1986

41

Generation of an S -Peptide via an N – S Acyl Shift Reaction in a TFA Solution

Nakamura, Ken’ichiroh, Sumida, Megumi, Kawakami, Toru, Vorherr, Thomas, Aimoto, Saburo

Journal:

Bulletin of the Chemical Society of Japan

Année:

2006

Langue:

english

Fichier:

PDF, 194 KB

english, 2006

42

Bioorthogonal Probes for the Study of MDM2-p53 Inhibitors in Cells and Development of High-Content Screening Assays for Drug Discovery

D'Alessandro, Pier Luca, Buschmann, Nicole, Kaufmann, Markus, Furet, Pascal, Baysang, Frederic, Brunner, Reto, Marzinzik, Andreas, Vorherr, Thomas, Stachyra, Therese-Marie, Ottl, Johannes, Lizos, Dimi

Journal:

Angewandte Chemie International Edition

Année:

2016

Langue:

english

Fichier:

PDF, 2.49 MB

english, 2016

43

Bioorthogonal Probes for the Study of MDM2-p53 Inhibitors in Cells and Development of High-Content Screening Assays for Drug Discovery

D'Alessandro, Pier Luca, Buschmann, Nicole, Kaufmann, Markus, Furet, Pascal, Baysang, Frederic, Brunner, Reto, Marzinzik, Andreas, Vorherr, Thomas, Stachyra, Therese-Marie, Ottl, Johannes, Lizos, Dimi

Journal:

Angewandte Chemie

Année:

2016

Langue:

english

Fichier:

PDF, 2.42 MB

english, 2016

44

A critical assessment of the synthesis and biological activity of p53/Hdm2 stapled peptide inhibitors

Wallbrecher, Rike, Chène, Patrick, Ruetz, Stephan, Stachyra, Therese, Vorherr, Thomas, Brock, Roland

Journal:

British Journal of Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 564 KB

english, 2017

45

Evaluating Cellular Drug Uptake with Fluorescent Sensor Proteins

Scarabelli, Silvia, Tan, Kui Thong, Griss, Rudolf, Hovius, Ruud, D’Alessandro, Pier Luca, Vorherr, Thomas, Johnsson, Kai

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 2.49 MB

english, 2017

46

H + -induced Membrane Insertion of Influenza Virus Hemagglutinin Involves the HA2 Amino-terminal Fusion Peptide but Not the Coiled Coil Region

Durrer, Peter, Galli, Carmela, Hoenke, Stefan, Corti, Chantal, Glück, Reinhard, Vorherr, Thomas, Brunner, Josef

Journal:

Journal of Biological Chemistry

Année:

1996

Langue:

english

Fichier:

PDF, 1.33 MB

english, 1996

47

Editor's mail

Connell, Elizabeth B., Benezra, Joseph, Vorherr, Helmuth, Smith, Trent W., Thomas, T. K.

Journal:

Postgraduate Medicine

Année:

1975

Langue:

english

Fichier:

PDF, 1.03 MB

english, 1975

48

Late-stage Functionalization of Peptides and Cyclopeptides using Organozinc reagents

Leroux, Marcel, Vorherr, Thomas, Lewis, Ian, Schaefer, Michael, Koch, Guido, Karaghiosoff, Konstantin, Knochel, Paul

Journal:

Angewandte Chemie International Edition

Année:

2019

Langue:

english

Fichier:

PDF, 1.35 MB

english, 2019

49

Bachem, a Swiss Speciality cGMP-Manufacturer: History and Future Prospects

Vorherr, Thomas, Dick, Fritz, Sax, Beat

Journal:

CHIMIA International Journal for Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 145 KB

english, 2005

50

Real-time imaging and quantification of peptide uptake in vitro and in vivo

Karatas, Hacer, Maric, Tamara, D'Alessandro, Pier Luca, Yevtodiyenko, Aleksey, Vorherr, Thomas, Hollingworth, Gregory J., Goun, Elena A.

Journal:

ACS Chemical Biology

Année:

2019

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2019